Carbon-based　nanomaterials　have　recently　attracted　tremendous　attention　in　adsorption,　separation　and　biological　fields.　However,　such　modification　is　not　always　straightforward　when　the　surface　is　not　chemically　reactive.　Given　this　reason,　most　carbon　materials　modification　processes　employ　reactive　linkers　or　coupling　agents,　which　are　complicated　and　time-consuming.　Herein,　we　report　on　a　dopamine-polyethyleneimine　(PEI)　coating　strategy　to　fabricate　micrometer-sized　magnetic　carbon　fiber　(MSMCF)-based　extracorporeal　blood-cleansing　sorbent　for　hemoperfusion.　Results　showed　that　the　dopamine/PEI-coated　MSMCF　had　a　twisted　fiber　shape　with　a　size　range　of　80-120　mu　m　in　diameter　and　porous　structure　with　a　specific　surface　area　of　146　m(2)　g(-1).　Adsorption　behavior　of　dopamine/PEI-modified　MSMCF　was　examined　by　using　bilirubin　as　a　toxin　model　compound.　Equilibrium　data　were　well　fitted　to　the　Langmuir　isotherm　model　with　a　maximal　adsorption　capacity　of　335.1　mg　g(-1)　at　ambient　temperature.　The　as-obtained　material　had　relatively　high　bilirubin　adsorption　selectivity　against　albumin　at　a　normal　albumin　concentration.　In　particular,　the　dopamine/PEI-coated　MSMCF　has　excellent　adsorption　capacity　and　hemocompatibility　compared　to　the　MSMCF　decorated　only　by　dopamine　or　PEI.　Therefore,　this　work　may　pave　the　way　for　enhancing　the　property　of　the　extracorporeal　blood-cleansing　sorbent　during　hemoperfusion.