The　stereo-lithography　technique　for　fabricating　biocompatible　polyethyleneglycol　diacrylate　(PEGDA)　hydrogel　with　a　controlled　accurate　architecture　is　developed　for　cartilage　tissue　engineering　application,　and　the　different　laser　scanning　parameters　for　single-line　hydrogel　or　2-D　layer　hydrogel　are　comparatively　investigated,　The　cure　parameters　of　the　single-line　and　2-D　layer　of　hydrogel　scaffold　are　affected　by　PEG(400)DA　content　of　the　solution,　the　laser　scanning　speed　and　hatch　space.　Hydrogel　scaffold　properties,　such　as　structure　accuracy,　composition,　and　water　absorption　and　compression　modulus　are　experimentally　confirmed.　The　results　showed　that:　Cure　depth　and　width　increase　positively　with　the　energy　dosage　of　laser　and　the　PEG(400)DA　content　of　solution;　Cure　depth　scales　inversely　with　the　hatch　space;　Water　absorption　decreases　and　the　compression　modulus　increases　as　the　PEG(400)DA　content　of　solution　varies　from　30%　to　60%.　The　optimal　laser　process　parameters　include:　0.1　W　laser　power,　1800　mm/s　laser　scanning　speed,　0.15　mm　hatch　space　and　30%　content　of　φ(PEG(400)DA)　solution,　customized　hydrogel　scaffold　of　knee　cartilage　was　obtained　with　191.67%　water　absorption　rate　and　0.75　MPa　average　compression　modulus.　The　stereo-lithographic　PEGDA　hydrogel　technique　perfectly　meets　the　requirements　for　cartilage　tissue　engineering.