Scanning　electrochemical　cell　microscopy　(SECCM),　is　a　local　electrochemical　measurement　technique　with　a　confined　area　of　a　surface,　especially　suited　for　the　electrochemical　mapping　with　topography　imaging　in　a　high-resolution　way.　Despite　its　wide　application,　the　droplet　evaporation/crystallization　of　its　nanopipet　tip　impacts　imaging　stability　for　the　large　surface　feature.　Here　we　use　single-barrel　SECCM　nanopipet　with　different　backpressure　to　increase　the　meniscus　droplet　thickness　and　then　improve　the　tip　perceptive　capability　and　imaging　stability,　avoiding　the　humidity　effect.　In　this　paper,　finite　element　method　and　experiment　are　first　employed　to　study　the　impact　of　the　droplet　height,　contact　radius,　and　half-cone　angle　of　the　nanopipet　tip　on　the　steady-state　current　when　the　meniscus　droplet　makes　contact　with　the　substrate　surface.　Further,　the　droplet　positioning　and　SECCM　scanning　experiments　are　conducted　to　compare　the　imaging　stability　of　the　conventional　and　pressure-applied　single-barrel　nanopipet　with　the　tip　opening　diameter　120　nm　in　different　humidity　environment.　The　experimental　results　demonstrate　that　the　pressure-applied　SECCM　nanopipet　can　sense　and　image　with　hopping　mode　in　lower　ambient　humidity　and　possess　higher　imaging　stability　(increase　by　more　than　40%　in　number　of　successful　images)　than　conventional　nanopipet　without　pressure.　©　2001-2012　IEEE.