Translated Title

Translated Abstract

BackgroundSchizophrenia　is　a　common　psychiatric　disease,　the　incidence　rate　of　0.5%　among　1%.　More　prolonged　course　repeatedly.　Depression　is　common　in　patients　with　symptoms　of　schizophrenia,　can　occur　in　different　periods　of　schizophrenia.　Johnson　through　the　2-year　follow-up　study　found　that　depression　can　extend　the　period　of　acute　symptoms　of　schizophrenia　and　to　2-fold　increased　risk　of　acute　relapse　of　schizophrenia　3　times　Falloon　found　that　depression　is　the　main　reason　for　hospital　admission　in　40%　of　patients　with　schizophrenia　depression　split　the　symptoms　are　more　likely　to　relapse.　Glazer　pointed　out　that　depressive　symptoms　and　poor　performance　of　schizophrenia　patients　with　social　contact,　including　the　difficulty　of　building　relationships　with　others　these　social　barriers　and　schizophrenia　depression,　premorbid　personality　and　the　insidious　onset　related　to　bad.　Schizophrenia　with　depression　often　associated　with　poor　prognosis,　and　functional　defects,　personal　pain,　a　higher　recurrence　rate,　and　then　even　higher　rate　of　suicide-related　hospitalization.　Significant　effect　on　depressive　symptoms　and　quality　of　life　of　patients　and　affect　the　clinical　course　of　many　diseases　and　recovery.　High　incidence　of　depressive　symptoms　of　schizophrenia,　and　the　severity　of　different　schizophrenia　depression　generally　higher　than　the　normal　healthy　population.　Some　studies　also　suggest　suicidal　behavior　in　schizophrenic　patients　a　higher　proportion　of　depressive　symptoms,　suicidal　behavior　and　depressive　symptoms　were　positively　correlated.　Depression　in　patients　with　chronic　schizophrenia　is　generally　higher　than　the　normal　population　incidence.　The　condition　of　depression　on　rehabilitation　of　patients　with　schizophrenia　have　a　greater　impact　and　quality　of　life.Research　AimThis　study　was　to　investigate　and　understand　the　incidence　of　depression　in　patients　with　chronic　schizophrenia　cases,　comparative　analysis　of　depression　in　patients　with　chronic　schizophrenia　related　factors,　of　depression　in　patients　with　chronic　schizophrenia　on　quality　of　life.　Drug　treatment　for　chronic　schizophrenia　and　chronic　schizophrenia　patients　in　order　to　reduce　the　incidence　of　depression　and　suicide,　to　promote　their　rehabilitation　to　provide　a　scientific　basis.MethodsXi‘an　Mental　Health　Center　from　June　2009　to　June　2010　patients　with　chronic　schizophrenia　were　hospitalized　as　the　research　object,　according　to　the　Chinese　Classification　and　Diagnostic　Criteria　of　Mental　Disease　(3rd　version)　(CCMD-3)　diagnostic　criteria　for　chronic　schizophrenia,　First,　the　psychiatrist　asked　about　the　history,　physical　examination　and　one　by　one　neuropsychiatric　examination.　And　then　by　two　or　more　psychiatrists　are　physicians　to　evaluate　their　symptoms,　respectively　positive　and　negative　scale　(PANSS),　the　treatment　of　symptoms　scale　(TESS),　Calgary　Depression　Scale　for　Schizophrenia　(CDSS)　overall　well-being　Scale　(GWB),　health　status　questionnaire　(SF-36)　and　other　objects　of　the　selected　evaluation.　With　SPSS18.0　data　for　statistical　analysis.ResultEnrolled　a　total　of　180　patients　with　chronic　schizophrenia,　88　patients　were　male,　female　92　cases.　Age　of　47.3　±　6.8　years.　Duration　18.4　±　8.0　years.　Number　of　hospitalization　5.0　±　2.8　times.　The　first　time,　age　28.9　±　8.5　years.　180　cases　of　patients　with　chronic　schizophrenia　PANSS　total　score　75.6　±　11.7　positive　scale　score　(P-PANSS)　18.0　±　5.9　negative　scale　score　(N-PANSS)　was　25.6　±　8.5　general　psychopathology　scale　score　(G-PANSS)　32.0　±　7.6　composite　scale　is　divided　into　-7.6　±　10.3.180　patients　with　chronic　schizophrenia　CDSS　score　of　0　to　11,　average　3.93±2.79　CDSS≥6　points,　59　cases,　score　6　to　11,　average　7.20±1.16.　Calculate　the　incidence　of　depressive　symptoms　in　patients　with　chronic　schizophrenia　was　32.78%.Will　be　associated　with　physical　illness,　marital　status,　insight,　family　economic　level,　physician-patient　relationship,　social　support,　disease　duration,　frequency　of　hospitalization,　PANSS,　P-PANSS,　N-PANSS,　composite　subscales,　TESS　into　multiple　Logistic　regression　analysis.　Results:　Depressive　symptoms　in　patients　with　chronic　schizophrenia,　the　impact　factors　for　N-PANSS　(p　=　0.006),　family　economic　level　(p　=　0.000),　TESS　points　(p　=　0.003),　marital　status　(p　=　0.003),　insight　(p　=　0.030)　and　PANSS　points　(p　=　0.025).　Insight　(OR　=　0.498)　and　household　economic　level　(OR　=　0.387)　in　patients　with　chronic　schizophrenia　protective　factors　of　depressive　symptoms　PANSS　(OR　=　1.059),　N-PANSS　(OR　=　1.101),　TESS　(OR　=　1.530)　and　unmarried　(OR　=　4.226)　or　without　a　spouse　(OR　=　3.024)　in　patients　with　chronic　schizophrenia　risk　factors　for　depressive　symptoms.Grouped　according　to　CDSS　no　depression　group　and　the　depression　group　and　the　SF-36,　respectively,　after　the　GWB　and　the　related　research,　tips　and　the　GWB　SF-36　was　negatively　correlated　with　the　CDSS　,　the　Correlation　coefficient　SF-36　is　-0.705,　GWB　is　-0.795,　CDSS　linear　regression　tips　and　SF-36,　respectively,　and　GWB　has　linear　regression,　description　of　life　in　patients　with　chronic　schizophrenia　and　subjective　well-being　of　poor　quality　and　low　on　depressive　symptoms　appear.Conclusion1.　Depressive　symptoms　in　patients　with　chronic　schizophrenia　incidence　rate　of　32.78%,　consistent　with　the　data　reported　at　home　and　abroad.　2.　Depressive　symptoms　in　patients　with　chronic　schizophrenia,　the　risk　factors　for　the　N-PANSS,　family　economic　level,　TESS　points,　marital　status,　insight,　PANSS　points　insight　and　the　family　economic　level　of　depressive　symptoms　in　patients　with　chronic　schizophrenia　protection　factors　PANSS,　N-PANSS,　TESS　or　without　a　spouse　and　unmarried　patients　with　chronic　schizophrenia　risk　factors　for　depressive　symptoms.3.　Direct　impact　on　depressive　symptoms　in　patients　with　chronic　schizophrenia　experience　a　sense　of　happiness,　depressive　symptoms　were　negatively　correlated　with　happiness,　decline　in　the　quality　of　life　in　patients　with　chronic　schizophrenia.

Translated Keyword

[]

Research Interests

Classification

Corresponding authors email