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Bilateral Interface Engineering toward Efficient 2D-3D Bulk Heterojunction Tin Halide Lead-Free Perovskite Solar Cells SCIE Scopus
期刊论文 | 2018 , 3 (3) , 713-+ | ACS ENERGY LETTERS
WoS CC Cited Count: 12
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Abstract :

As a promising substitute for toxic lead-based perovskite, tin (Sn)-based halide perovskite has drawn much attention for photovoltaic applications. However, unsatisfied open-circuit voltage (V-OC) and fill factor (FF) values of the available Sn-based perovskite solar cells (PSCs) remain a lingering cloud. In this work, we report a bilateral interfacial engineering strategy to fabricate 2D-3D bulk heterojunction Sn-based perovskite solar cells. Specifically, large cation PEAI and bifunctional LiF are evaporated at the bilateral interfaces of a FASnI(3) film. The presence of PEAI improves the V-OC and FF of the PSCs via improved surface coverage and the formed 2D-3D bulk heterojunction structure, while the bifunctional LiF (i) lowers the work function of PEDOT:PSS and (ii) facilitates hole extraction at the ITO/PEDOT:PSS interface. This strategy enabled a power conversion efficiency (PCE) of 6.98% with a V-OC of 0.47 V and FF of 0.74. Our findings will add critical building bricks toward efficient Sn-based PSCs.

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GB/T 7714 Ran, Chenxin , Xi, Jun , Gao, Weiyin et al. Bilateral Interface Engineering toward Efficient 2D-3D Bulk Heterojunction Tin Halide Lead-Free Perovskite Solar Cells [J]. | ACS ENERGY LETTERS , 2018 , 3 (3) : 713-+ .
MLA Ran, Chenxin et al. "Bilateral Interface Engineering toward Efficient 2D-3D Bulk Heterojunction Tin Halide Lead-Free Perovskite Solar Cells" . | ACS ENERGY LETTERS 3 . 3 (2018) : 713-+ .
APA Ran, Chenxin , Xi, Jun , Gao, Weiyin , Yuan, Fang , Lei, Ting , Jiao, Bo et al. Bilateral Interface Engineering toward Efficient 2D-3D Bulk Heterojunction Tin Halide Lead-Free Perovskite Solar Cells . | ACS ENERGY LETTERS , 2018 , 3 (3) , 713-+ .
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Dietary salt blunts vasodilation by stimulating epithelial sodium channels in endothelial cells from salt-sensitive Dahl rats SCIE PubMed
期刊论文 | 2018 , 175 (8) , 1305-1317 | BRITISH JOURNAL OF PHARMACOLOGY
WoS CC Cited Count: 5
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Abstract :

Background and PurposeOur recent studies show that the reduced activity of epithelial sodium channels (ENaC) in endothelial cells accounts for the adaptation of vasculature to salt in Sprague-Dawley rats. The present study examines a hypothesis that enhanced ENaC activity mediates the loss of vasorelaxation in Dahl salt-sensitive (SS) rats. Experimental ApproachWe used the cell-attached patch-clamp technique to record ENaC activity in split-open mesenteric arteries. Western blot and immunofluorescence staining were used to evaluate the levels of aldosterone, ENaC, eNOS and NO. Blood pressure was measured with the tail-cuff method and the artery relaxation was measured with the wire myograph assay. Key ResultsHigh-salt (HS) diet significantly increased plasma aldosterone and ENaC activity in the endothelial cells of Dahl SS rats. The endothelium-dependent artery relaxation was blunted by HS challenge in these rats. Amiloride, a potent blocker of ENaC, increased both phosphorylated eNOS and NO and therefore prevented the HS-induced loss of vasorelaxation. As, in SS rats, endogenous aldosterone was already elevated by HS challenge, exogenous aldosterone did not further elevate ENaC activity in the rats fed with HS. Eplerenone, a mineralocorticoid receptor antagonist, attenuated the effects of HS on both ENaC activity and artery relaxation. Conclusions and ImplicationsThese data suggest that HS diet blunts artery relaxation and causes hypertension via a pathway associated with aldosterone-dependent activation of ENaC in endothelial cells. This pathway provides one of the mechanisms by which HS causes hypertension in Dahl SS rats. Linked ArticlesThis article is part of a themed section on Spotlight on Small Molecules in Cardiovascular Diseases. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v175.8/issuetoc

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GB/T 7714 Wang, Zi-Rui , Liu, Hui-Bin , Sun, Ying-Ying et al. Dietary salt blunts vasodilation by stimulating epithelial sodium channels in endothelial cells from salt-sensitive Dahl rats [J]. | BRITISH JOURNAL OF PHARMACOLOGY , 2018 , 175 (8) : 1305-1317 .
MLA Wang, Zi-Rui et al. "Dietary salt blunts vasodilation by stimulating epithelial sodium channels in endothelial cells from salt-sensitive Dahl rats" . | BRITISH JOURNAL OF PHARMACOLOGY 175 . 8 (2018) : 1305-1317 .
APA Wang, Zi-Rui , Liu, Hui-Bin , Sun, Ying-Ying , Hu, Qing-Qing , Li, Yu-Xia , Zheng, Wei-Wan et al. Dietary salt blunts vasodilation by stimulating epithelial sodium channels in endothelial cells from salt-sensitive Dahl rats . | BRITISH JOURNAL OF PHARMACOLOGY , 2018 , 175 (8) , 1305-1317 .
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Recent advances in siRNA delivery for cancer therapy using smart nanocarriers SCIE PubMed Scopus
期刊论文 | 2018 , 23 (4) , 900-911 | DRUG DISCOVERY TODAY
WoS CC Cited Count: 6 SCOPUS Cited Count: 8
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Abstract :

Small interfering RNAs (siRNAs) can selectively target and downregulate disease-causing genes, holding great promise in treating human diseases, especially malignant cancers. However, how to efficiently deliver siRNAs into target cell cytosol is a problem that has hindered their clinical application. Here, we review the recent strategies for siRNA delivery on the basis of smart nanocarriers by using stimuli responsive materials. We highlight the rationales of how to design smart nanocarriers responsive to physiological and external stimuli to improve the delivery efficiency, targeting precision and gene silencing efficacy. Finally, we provide an outlook on the fundamental limitation for clinical translation of siRNA-based nanomedicine that should be overcome by the combination of chemistry, biology, material and medical science.

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GB/T 7714 Zhang, Penghui , An, Keli , Duan, Xiaoman et al. Recent advances in siRNA delivery for cancer therapy using smart nanocarriers [J]. | DRUG DISCOVERY TODAY , 2018 , 23 (4) : 900-911 .
MLA Zhang, Penghui et al. "Recent advances in siRNA delivery for cancer therapy using smart nanocarriers" . | DRUG DISCOVERY TODAY 23 . 4 (2018) : 900-911 .
APA Zhang, Penghui , An, Keli , Duan, Xiaoman , Xu, Hao , Li, Fei , Xu, Feng . Recent advances in siRNA delivery for cancer therapy using smart nanocarriers . | DRUG DISCOVERY TODAY , 2018 , 23 (4) , 900-911 .
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Development of a predictive model for Clostridium difficile infection incidence in hospitals using Gaussian mixture model and Dempster-Shafer theory EI SCIE Scopus
期刊论文 | 2018 , 32 (6) , 1743-1758 | STOCHASTIC ENVIRONMENTAL RESEARCH AND RISK ASSESSMENT
WoS CC Cited Count: 8 SCOPUS Cited Count: 10
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Abstract :

Clostridium difficile infection is one of the major patient safety concerns in hospitals worldwide. Clostridium difficile infection can have high economic burden to patients, hospitals, and government. Limited work has been done in the area of predictive modeling. In this article, A new predictive model based on Gaussian mixture model and Dempster-Shafter theory is proposed to predict Clostridium difficile infection incidence in hospitals. First, the Gaussian mixture model and expectation-maximization algorithms are used to generate explicit probability criteria of risk factors based on the given data. Second, Dempster-Shafter theory is used to predict the Clostridium difficile infection incidence based on the generated probability criteria that have different beliefs attributing to their different credits. The main procedure includes (1) generate the probability criteria model using Gaussian mixture model and expectation-maximization algorithm; (2) determine the credit of the probability criteria; (3) generate the basic probability assignment; (4) discount the evidences; (5) aggregate the evidences using Dempster combining rule; (6) predict Clostridium difficile infection incidence using pignistic probability transformation. Results show that the model has a higher accuracy than an existing model. The proposed model can generate the criteria ratings of risk factors automatically, which would potentially prevent the imprecision caused by the subjective judgement of experts. The proposed model can assist risk managers and hospital administrators in the prediction and control of Clostridium difficile infection incidence with optimizing their resources.

Keyword :

Predictive model Clostridium difficile infection Dempster-Shafer theory Gaussian mixture model Unsupervised learning

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GB/T 7714 Kang, Bingyi , Chhipi-Shrestha, Gyan , Deng, Yong et al. Development of a predictive model for Clostridium difficile infection incidence in hospitals using Gaussian mixture model and Dempster-Shafer theory [J]. | STOCHASTIC ENVIRONMENTAL RESEARCH AND RISK ASSESSMENT , 2018 , 32 (6) : 1743-1758 .
MLA Kang, Bingyi et al. "Development of a predictive model for Clostridium difficile infection incidence in hospitals using Gaussian mixture model and Dempster-Shafer theory" . | STOCHASTIC ENVIRONMENTAL RESEARCH AND RISK ASSESSMENT 32 . 6 (2018) : 1743-1758 .
APA Kang, Bingyi , Chhipi-Shrestha, Gyan , Deng, Yong , Mori, Julie , Hewage, Kasun , Sadiq, Rehan . Development of a predictive model for Clostridium difficile infection incidence in hospitals using Gaussian mixture model and Dempster-Shafer theory . | STOCHASTIC ENVIRONMENTAL RESEARCH AND RISK ASSESSMENT , 2018 , 32 (6) , 1743-1758 .
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Evaluation of economic transformation and upgrading of resource-based cities in Shaanxi province based on an improved TOPSIS method EI SSCI SCIE Scopus
期刊论文 | 2018 , 37 , 232-240 | SUSTAINABLE CITIES AND SOCIETY
WoS CC Cited Count: 7 SCOPUS Cited Count: 10
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Abstract :

The economic transformation and upgrading of resource-based cities is an overleaping development caused by technological progress and institutional change. Traditional models do not comprehensively evaluate the development level of resource-based cities. This study establishes a comprehensive index system from three aspects: economic adjustment, social progress and environmental improvement. An improved TOPSIS method and sequence weighting are applied to evaluate the level of transformation and upgrading of six resource-based cities in Shaanxi province from 2001 to 2015. The results indicate that six resource-based cities in Shaanxi Province have made an improvement in economic adjustment, social progress and environmental improvement. The economic adjustment effect is not obvious and there is a downward trend in some cities. The social development level of six resource-based cities increases significantly. The structural contradictions in the economy has not been fundamentally resolved. The effect of environmental improvement shows an evident increasing trend. All the six cities in environmental improvement achieve successful transformation.

Keyword :

Economic transformation and upgrading Shaanxi province Resource-based city TOPSIS method

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GB/T 7714 Chen, Wei , Shen, Yue , Wang, Yanan . Evaluation of economic transformation and upgrading of resource-based cities in Shaanxi province based on an improved TOPSIS method [J]. | SUSTAINABLE CITIES AND SOCIETY , 2018 , 37 : 232-240 .
MLA Chen, Wei et al. "Evaluation of economic transformation and upgrading of resource-based cities in Shaanxi province based on an improved TOPSIS method" . | SUSTAINABLE CITIES AND SOCIETY 37 (2018) : 232-240 .
APA Chen, Wei , Shen, Yue , Wang, Yanan . Evaluation of economic transformation and upgrading of resource-based cities in Shaanxi province based on an improved TOPSIS method . | SUSTAINABLE CITIES AND SOCIETY , 2018 , 37 , 232-240 .
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Synthesis, functionalization, and applications of metal-organic frameworks in biomedicine EI SCIE PubMed Scopus
期刊论文 | 2018 , 47 (7) , 2114-2133 | DALTON TRANSACTIONS
WoS CC Cited Count: 9
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Metal-organic frameworks (MOFs), also known as coordination polymers, have attracted extensive research interest in the past few decades due to their unique physical structures and potentially vast applications. In this review, we outline the recent progress in the synthesis, functionalization and applications of MOFs in biomedicine, mainly focusing on two promising, yet challenging areas, i.e., drug delivery and biosensing applications. A major challenge is the proper functionalization of MOFs with demanding properties suitable for biomedical applications. Extensive studies on MOFs in biomedicine have led to substantial progress in the control of key properties of MOFs such as toxicity, size and shape, and biological stability. Due to their flexible composition, pore size and easy functionalization properties, MOFs can be utilized as key components for the development of various functional systems, and their applications in drug delivery and biosensing are reviewed. Future trends and perspectives in these research areas are also outlined.

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GB/T 7714 Chen, Wei , Wu, Chunsheng . Synthesis, functionalization, and applications of metal-organic frameworks in biomedicine [J]. | DALTON TRANSACTIONS , 2018 , 47 (7) : 2114-2133 .
MLA Chen, Wei et al. "Synthesis, functionalization, and applications of metal-organic frameworks in biomedicine" . | DALTON TRANSACTIONS 47 . 7 (2018) : 2114-2133 .
APA Chen, Wei , Wu, Chunsheng . Synthesis, functionalization, and applications of metal-organic frameworks in biomedicine . | DALTON TRANSACTIONS , 2018 , 47 (7) , 2114-2133 .
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Efficacy and Safety of Tamsulosin in Medical Expulsive Therapy for Distal Ureteral Stones with Renal Colic: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial SCIE PubMed Scopus
期刊论文 | 2018 , 73 (3) , 385-391 | EUROPEAN UROLOGY
WoS CC Cited Count: 17 SCOPUS Cited Count: 21
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Abstract :

Background: Recent large high-quality trials have questioned the clinical effectiveness of medical expulsive therapy using tamsulosin for ureteral stones. Objective: To evaluate the efficacy and safety of tamsulosin for distal ureteral stones compared with placebo. Design, setting, and participants: We conducted a double-blind, placebo-controlled study of 3296 patients with distal ureteral stones, across 30 centers, to evaluate the efficacy and safety of tamsulosin. Intervention: Participants were randomly assigned (1:1) into tamsulosin (0.4 mg) or placebo groups for 4 wk. Outcome measurements and statistical analysis: The primary end point of analysis was the overall stone expulsion rate, defined as stone expulsion, confirmed by negative findings on computed tomography, over a 28-d surveillance period. Secondary end points included time to stone expulsion, use of analgesics, and incidence of adverse events. Results and limitations: Among 3450 patients randomized between September 1, 2011, and August 31, 2013, 3296 (96%) were included in the primary analysis. Tamsulosin benefits from a higher stone expulsion rate than the placebo (86% vs 79%; p < 0.001) for distal ureteral stones. Subgroup analysis identified a specific benefit of tamsulosin for the treatment of large distal ureteral stones (>5 mm). Considering the secondary end points, tamsulosin-treated patients reported a shorter time to expulsion (p < 0.001), required lower use of analgesics compared with placebo (p < 0.001), and significantly relieved renal colic (p < 0.001). No differences in the incidence of adverse events were identified between the two groups. Conclusions: Our data suggest that tamsulosin use benefits distal ureteral stones in facilitating stone passage and relieving renal colic. Subgroup analyses find that tamsulosin provides a superior expulsion rate for stones >5 mm, but no effect for stones <= 5 mm. (c) 2017 European Association of Urology. Published by Elsevier B.V. All rights reserved.

Keyword :

Renal colic Distal ureteral stones Medical expulsive therapy Adrenergic alpha blockers Tamsulosin

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GB/T 7714 Ye, Zhangqun , Zeng, Guohua , Yang, Huan et al. Efficacy and Safety of Tamsulosin in Medical Expulsive Therapy for Distal Ureteral Stones with Renal Colic: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial [J]. | EUROPEAN UROLOGY , 2018 , 73 (3) : 385-391 .
MLA Ye, Zhangqun et al. "Efficacy and Safety of Tamsulosin in Medical Expulsive Therapy for Distal Ureteral Stones with Renal Colic: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial" . | EUROPEAN UROLOGY 73 . 3 (2018) : 385-391 .
APA Ye, Zhangqun , Zeng, Guohua , Yang, Huan , Tang, Kun , Zhang, Xiaochun , Li, Hong et al. Efficacy and Safety of Tamsulosin in Medical Expulsive Therapy for Distal Ureteral Stones with Renal Colic: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial . | EUROPEAN UROLOGY , 2018 , 73 (3) , 385-391 .
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Umbilical Cord Mesenchymal Stem Cell Treatment for Crohn's Disease: A Randomized Controlled Clinical Trial SCIE PubMed Scopus
期刊论文 | 2018 , 12 (1) , 73-78 | GUT AND LIVER
WoS CC Cited Count: 4 SCOPUS Cited Count: 5
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Abstract :

Background/Aims: Stem cell therapy has been applied to treat a variety of autoimmune diseases, including Crohn's disease (CD), but few studies have examined the use of umbilical cord mesenchymal stem cells (UC-MSCs). This trial sought to investigate the efficacy and safety of UC-MSCs for the treatment of CD. Methods: Eighty-two patients who had been diagnosed with CD and had received steroid maintenance therapy for more than 6 months were included in this study. Forty-one patients were randomly selected to receive a total of four peripheral intravenous infusions of 1x10(6) UC-MSCs/kg, with one infusion per week. Patients were followed up for 12 months. The Crohn's disease activity index (CDAI), Harvey-Bradshaw index (HBI), and corticosteroid dosage were assessed. Results: Twelve months after treatment, the CDAI, HBI, and corticosteroid dosage had decreased by 62.5 +/- 23.2, 3.4 +/- 1.2, and 4.2 +/- 0.84 mg/day, respectively, in the UC-MSC group and by 23.6 +/- 12.4, 1.2 +/- 0.58, and 1.2 +/- 0.35 mg/day, respectively, in the control group (p<0.01, p<0.05, and p<0.05 for UC-MSC vs control, respectively). Four patients developed a fever after cell infusion. No serious adverse events were observed. Conclusions: UC-MSCs were effective in the treatment of CD and produced mild side effects.

Keyword :

Mesenchymal stromal cells Autoimmune Cellular therapy Umbilical cord Crohn disease

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GB/T 7714 Zhang, Jian , Lv, Samei , Liu, Xiaojing et al. Umbilical Cord Mesenchymal Stem Cell Treatment for Crohn's Disease: A Randomized Controlled Clinical Trial [J]. | GUT AND LIVER , 2018 , 12 (1) : 73-78 .
MLA Zhang, Jian et al. "Umbilical Cord Mesenchymal Stem Cell Treatment for Crohn's Disease: A Randomized Controlled Clinical Trial" . | GUT AND LIVER 12 . 1 (2018) : 73-78 .
APA Zhang, Jian , Lv, Samei , Liu, Xiaojing , Song, Bin , Shi, Liping . Umbilical Cord Mesenchymal Stem Cell Treatment for Crohn's Disease: A Randomized Controlled Clinical Trial . | GUT AND LIVER , 2018 , 12 (1) , 73-78 .
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An Empirical Study on Design Partner Selection in Green Product Collaboration Design SSCI SCIE Scopus
期刊论文 | 2018 , 10 (1) | SUSTAINABILITY
WoS CC Cited Count: 4 SCOPUS Cited Count: 4
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Green production has become an important issue in PCD (Product Collaboration Design) for almost every enterprise, and will determine the sustainability of enterprises in the long term. The choice of design partner is a necessary condition in order to achieve green production. For the uncertain, fuzzy, and dynamic information such as unknown indices and weights, fuzzy semantics, and dynamic time factors in GPCD (Green Product Collaboration Design), a two-stage dynamic hybrid MADM (Multi-Attribute Decision Making) approach based on fuzzy DEMATEL (Decision-Making and Trial Evaluation Laboratory), fuzzy KMA (Karnik-Mendel Algorithm), and fuzzy VIKOR (VlseKriterjumska Optimizacija I Kompromisno Resenje) was proposed. In the first stage, fuzzy DEMATEL was used to determine the evaluation indices. Then, in the second stage, to accurately depict the dynamic information generated by the different phases of a product design, the dynamic evaluation method based on fuzzy theories was employed, and the weights of the indices were calculated by fuzzy KMA, then sorted by fuzzy VIKOR. Finally, a case study and a comparative analysis wre provided to illustrate the effectiveness of the proposed approach.

Keyword :

green product design partner selection sustainable operation fuzzy KMA sustainability fuzzy VIKOR dynamic hybrid MADM fuzzy DEMATEL

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GB/T 7714 Liu, Aijun , Liu, Haiyang , Xiao, Yaxuan et al. An Empirical Study on Design Partner Selection in Green Product Collaboration Design [J]. | SUSTAINABILITY , 2018 , 10 (1) .
MLA Liu, Aijun et al. "An Empirical Study on Design Partner Selection in Green Product Collaboration Design" . | SUSTAINABILITY 10 . 1 (2018) .
APA Liu, Aijun , Liu, Haiyang , Xiao, Yaxuan , Tsai, Sang-Bing , Lu, Hui . An Empirical Study on Design Partner Selection in Green Product Collaboration Design . | SUSTAINABILITY , 2018 , 10 (1) .
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Plastid Genome Comparative and Phylogenetic Analyses of the Key Genera in Fagaceae: Highlighting the Effect of Codon Composition Bias in Phylogenetic Inference SCIE PubMed Scopus
期刊论文 | 2018 , 9 | FRONTIERS IN PLANT SCIENCE
WoS CC Cited Count: 5 SCOPUS Cited Count: 6
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Fagaceae is one of the largest and economically important taxa within Fagales. Considering the incongruence among inferences from plastid and nuclear genes in the previous Fagaceae phylogeny studies, we assess the performance of plastid phylogenomics in this complex family. We sequenced and assembled four complete plastid genomes (Fagus engleriana, Quercus spinosa, Quercus aquifolioldes, and Quercus glauca) using reference-guided assembly approach. All of the other 12 published plastid genomes in Fagaceae were retrieved for genomic analyses (including repeats, sequence divergence and codon usage) and phylogenetic inference. The genomic analyses reveal that plastid genomes in Fagaceae are conserved. Comparing the phylogenetic relationships of the key genera in Fagaceae inferred from different codon positions and gene function datasets, we found that the first two codon sites dataset recovered nearly all relationships and received high support. Thus, the result suggested that codon composition bias had great influence on Fagaceae phylogenetic inference. Our study not only provides basic understanding of Fagaceae plastid genomes, but also illuminates the effectiveness of plastid phylogenomics in resolving relationships of this intractable family.

Keyword :

plastid genome phylogenomics codon composition bias Fagaceae topological incongruence

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GB/T 7714 Yang, Yanci , Zhu, Juan , Feng, Li et al. Plastid Genome Comparative and Phylogenetic Analyses of the Key Genera in Fagaceae: Highlighting the Effect of Codon Composition Bias in Phylogenetic Inference [J]. | FRONTIERS IN PLANT SCIENCE , 2018 , 9 .
MLA Yang, Yanci et al. "Plastid Genome Comparative and Phylogenetic Analyses of the Key Genera in Fagaceae: Highlighting the Effect of Codon Composition Bias in Phylogenetic Inference" . | FRONTIERS IN PLANT SCIENCE 9 (2018) .
APA Yang, Yanci , Zhu, Juan , Feng, Li , Zhou, Tao , Bei, Guoding , Yang, Jia et al. Plastid Genome Comparative and Phylogenetic Analyses of the Key Genera in Fagaceae: Highlighting the Effect of Codon Composition Bias in Phylogenetic Inference . | FRONTIERS IN PLANT SCIENCE , 2018 , 9 .
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